Introduction of keratolytic agents commonly used in cosmetic ingredients

The rate of epidermal metabolism during skin aging is slowed down, and the stratum corneum often cannot be detached in time, thus making the skin surface rough. The use of mild horny exfoliants can promote the weakening of the intercellular binding force in the aging stratum corneum, accelerate the rate of cell renewal and promote the death of cells. The purpose of improving the skin condition by detachment, etc., has the effect of making the skin surface smooth, delicate, and soft, and it has wrinkle-removing and anti-aging effects on the skin.

The horny exfoliants commonly used in cosmetic ingredients are a-hydroxy acids (AHAs) and B-hydroxy acids (BHA), and a-hydroxy acids include glycolic acid, lactic acid, citric acid, malic acid, mandelic acid, and tartaric acid, most of which are present in Fruits (lemon, apples, grapes, etc.) are commonly referred to as fruit acids. High concentrations of AHAs can be used for chemical exfoliation of the epidermis, while low concentrations of AHAs can thicken the active epidermis, at the same time can reduce the adhesion of epidermal keratinocytes and increase the content of dermal mucopolysaccharides, hyaluronic acid, so that collagen formation increases and decreases. Skin wrinkles increase the smoothness and tenacity of the skin, thereby improving the performance of photoaging-induced skin aging.

B-hydroxy acids are mainly extracted from naturally occurring plants such as willow bark, holly leaves and birch bark. They are fat-soluble new-generation fruit acids that have stronger affinity and penetration than traditional water-soluble fruit acids. Force, with a sustained release effect, can dissolve the keratinized substance in the hair follicle mouth, and make the pores shrink. The use concentration is only one-fifth that of traditional fruit acid, which is mild and efficient. At present, the "botanical essence" mentioned in cosmetics often has a certain exfoliative effect.